sirna-design tool Search Results


sirna-design tool  (GenScript corporation)
90
GenScript corporation sirna-design tool
Sirna Design Tool, supplied by GenScript corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/sirna-design tool/product/GenScript corporation
Average 90 stars, based on 1 article reviews
sirna-design tool - by Bioz Stars, 2026-03
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sirna-design tools  (Eurofins)
90
Eurofins sirna-design tools
Sirna Design Tools, supplied by Eurofins, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/sirna-design tools/product/Eurofins
Average 90 stars, based on 1 article reviews
sirna-design tools - by Bioz Stars, 2026-03
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sirna design tool  (Qiagen)
90
Qiagen sirna design tool
Sirna Design Tool, supplied by Qiagen, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/sirna design tool/product/Qiagen
Average 90 stars, based on 1 article reviews
sirna design tool - by Bioz Stars, 2026-03
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sirna design tool  (Eurofins Genomics)
90
Eurofins Genomics sirna design tool
(A) H1-0 expression determined by RT-qPCR and representative Western Blot of REH cells treated for 48 hours with a non-targeting <t>siRNA</t> pool (siCtrl) or H1-0 -targeting siRNA pools siH1-0_1 or siH1- 0_2. Data is presented as the mean ± standard deviation. (B) Enrichment map of gene sets enriched in siCtrl REH cells compared to <t>siRNA-mediated</t> <t>knockdown</t> of H1-0 (cut-offs: p<0.005, false discovery rate (FDR) q-value<0.1) using the canonical pathways gene set collection (Human MSigDB Collections). No significantly enriched gene sets were found in siH1-0 REH cells using the indicated cut-offs. Groups of similar pathways are indicated. (C) Ingenuity Pathway analysis (IPA, QIAGEN) of upstream regulators significantly enriched in both siH1-0_1 versus siCtrl and siH1-0_2 versus siCtrl (p<0.05). (D) GSEA results of siH1-0 versus siCtrl using a published geneset of 103 significantly upregulated genes in both REH and AT-2 cells upon ETV6::RUNX1 knockdown (cut-offs: log2 fold change >0.9 and adjusted p<0.05). Normalized enrichment score (NES) and FDR are indicated. (E) GSEA of siH1-0 versus siCtrl using the HALLMARK_P53_PATHWAY gene set derived from Human MSigDB Collections. (F) RNA expression levels of EPOR , RAG1 and MDM2 determined by RNA-seq in siCtrl and siH1-0 REH. (G) Pearson correlation of H1-0 expression with EPOR or RAG1 expression in ETV6::RUNX1 + BCP-ALL patient samples derived from the PeCan St. Jude cloud (n=87, ( ; )).
Sirna Design Tool, supplied by Eurofins Genomics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/sirna design tool/product/Eurofins Genomics
Average 90 stars, based on 1 article reviews
sirna design tool - by Bioz Stars, 2026-03
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sirna design tool xeragox  (Qiagen)
90
Qiagen sirna design tool xeragox
(A) H1-0 expression determined by RT-qPCR and representative Western Blot of REH cells treated for 48 hours with a non-targeting <t>siRNA</t> pool (siCtrl) or H1-0 -targeting siRNA pools siH1-0_1 or siH1- 0_2. Data is presented as the mean ± standard deviation. (B) Enrichment map of gene sets enriched in siCtrl REH cells compared to <t>siRNA-mediated</t> <t>knockdown</t> of H1-0 (cut-offs: p<0.005, false discovery rate (FDR) q-value<0.1) using the canonical pathways gene set collection (Human MSigDB Collections). No significantly enriched gene sets were found in siH1-0 REH cells using the indicated cut-offs. Groups of similar pathways are indicated. (C) Ingenuity Pathway analysis (IPA, QIAGEN) of upstream regulators significantly enriched in both siH1-0_1 versus siCtrl and siH1-0_2 versus siCtrl (p<0.05). (D) GSEA results of siH1-0 versus siCtrl using a published geneset of 103 significantly upregulated genes in both REH and AT-2 cells upon ETV6::RUNX1 knockdown (cut-offs: log2 fold change >0.9 and adjusted p<0.05). Normalized enrichment score (NES) and FDR are indicated. (E) GSEA of siH1-0 versus siCtrl using the HALLMARK_P53_PATHWAY gene set derived from Human MSigDB Collections. (F) RNA expression levels of EPOR , RAG1 and MDM2 determined by RNA-seq in siCtrl and siH1-0 REH. (G) Pearson correlation of H1-0 expression with EPOR or RAG1 expression in ETV6::RUNX1 + BCP-ALL patient samples derived from the PeCan St. Jude cloud (n=87, ( ; )).
Sirna Design Tool Xeragox, supplied by Qiagen, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/sirna design tool xeragox/product/Qiagen
Average 90 stars, based on 1 article reviews
sirna design tool xeragox - by Bioz Stars, 2026-03
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sirna design tool  (Microsynth ag)
90
Microsynth ag sirna design tool
(A) H1-0 expression determined by RT-qPCR and representative Western Blot of REH cells treated for 48 hours with a non-targeting <t>siRNA</t> pool (siCtrl) or H1-0 -targeting siRNA pools siH1-0_1 or siH1- 0_2. Data is presented as the mean ± standard deviation. (B) Enrichment map of gene sets enriched in siCtrl REH cells compared to <t>siRNA-mediated</t> <t>knockdown</t> of H1-0 (cut-offs: p<0.005, false discovery rate (FDR) q-value<0.1) using the canonical pathways gene set collection (Human MSigDB Collections). No significantly enriched gene sets were found in siH1-0 REH cells using the indicated cut-offs. Groups of similar pathways are indicated. (C) Ingenuity Pathway analysis (IPA, QIAGEN) of upstream regulators significantly enriched in both siH1-0_1 versus siCtrl and siH1-0_2 versus siCtrl (p<0.05). (D) GSEA results of siH1-0 versus siCtrl using a published geneset of 103 significantly upregulated genes in both REH and AT-2 cells upon ETV6::RUNX1 knockdown (cut-offs: log2 fold change >0.9 and adjusted p<0.05). Normalized enrichment score (NES) and FDR are indicated. (E) GSEA of siH1-0 versus siCtrl using the HALLMARK_P53_PATHWAY gene set derived from Human MSigDB Collections. (F) RNA expression levels of EPOR , RAG1 and MDM2 determined by RNA-seq in siCtrl and siH1-0 REH. (G) Pearson correlation of H1-0 expression with EPOR or RAG1 expression in ETV6::RUNX1 + BCP-ALL patient samples derived from the PeCan St. Jude cloud (n=87, ( ; )).
Sirna Design Tool, supplied by Microsynth ag, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/sirna design tool/product/Microsynth ag
Average 90 stars, based on 1 article reviews
sirna design tool - by Bioz Stars, 2026-03
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sirna design tool; custom sirna synthesis  (Xeragon Inc)
90
Xeragon Inc sirna design tool; custom sirna synthesis
(A) H1-0 expression determined by RT-qPCR and representative Western Blot of REH cells treated for 48 hours with a non-targeting <t>siRNA</t> pool (siCtrl) or H1-0 -targeting siRNA pools siH1-0_1 or siH1- 0_2. Data is presented as the mean ± standard deviation. (B) Enrichment map of gene sets enriched in siCtrl REH cells compared to <t>siRNA-mediated</t> <t>knockdown</t> of H1-0 (cut-offs: p<0.005, false discovery rate (FDR) q-value<0.1) using the canonical pathways gene set collection (Human MSigDB Collections). No significantly enriched gene sets were found in siH1-0 REH cells using the indicated cut-offs. Groups of similar pathways are indicated. (C) Ingenuity Pathway analysis (IPA, QIAGEN) of upstream regulators significantly enriched in both siH1-0_1 versus siCtrl and siH1-0_2 versus siCtrl (p<0.05). (D) GSEA results of siH1-0 versus siCtrl using a published geneset of 103 significantly upregulated genes in both REH and AT-2 cells upon ETV6::RUNX1 knockdown (cut-offs: log2 fold change >0.9 and adjusted p<0.05). Normalized enrichment score (NES) and FDR are indicated. (E) GSEA of siH1-0 versus siCtrl using the HALLMARK_P53_PATHWAY gene set derived from Human MSigDB Collections. (F) RNA expression levels of EPOR , RAG1 and MDM2 determined by RNA-seq in siCtrl and siH1-0 REH. (G) Pearson correlation of H1-0 expression with EPOR or RAG1 expression in ETV6::RUNX1 + BCP-ALL patient samples derived from the PeCan St. Jude cloud (n=87, ( ; )).
Sirna Design Tool; Custom Sirna Synthesis, supplied by Xeragon Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/sirna design tool; custom sirna synthesis/product/Xeragon Inc
Average 90 stars, based on 1 article reviews
sirna design tool; custom sirna synthesis - by Bioz Stars, 2026-03
90/100 stars
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simax sirna design tool  (Eurofins Genomics)
90
Eurofins Genomics simax sirna design tool
(A) H1-0 expression determined by RT-qPCR and representative Western Blot of REH cells treated for 48 hours with a non-targeting <t>siRNA</t> pool (siCtrl) or H1-0 -targeting siRNA pools siH1-0_1 or siH1- 0_2. Data is presented as the mean ± standard deviation. (B) Enrichment map of gene sets enriched in siCtrl REH cells compared to <t>siRNA-mediated</t> <t>knockdown</t> of H1-0 (cut-offs: p<0.005, false discovery rate (FDR) q-value<0.1) using the canonical pathways gene set collection (Human MSigDB Collections). No significantly enriched gene sets were found in siH1-0 REH cells using the indicated cut-offs. Groups of similar pathways are indicated. (C) Ingenuity Pathway analysis (IPA, QIAGEN) of upstream regulators significantly enriched in both siH1-0_1 versus siCtrl and siH1-0_2 versus siCtrl (p<0.05). (D) GSEA results of siH1-0 versus siCtrl using a published geneset of 103 significantly upregulated genes in both REH and AT-2 cells upon ETV6::RUNX1 knockdown (cut-offs: log2 fold change >0.9 and adjusted p<0.05). Normalized enrichment score (NES) and FDR are indicated. (E) GSEA of siH1-0 versus siCtrl using the HALLMARK_P53_PATHWAY gene set derived from Human MSigDB Collections. (F) RNA expression levels of EPOR , RAG1 and MDM2 determined by RNA-seq in siCtrl and siH1-0 REH. (G) Pearson correlation of H1-0 expression with EPOR or RAG1 expression in ETV6::RUNX1 + BCP-ALL patient samples derived from the PeCan St. Jude cloud (n=87, ( ; )).
Simax Sirna Design Tool, supplied by Eurofins Genomics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/simax sirna design tool/product/Eurofins Genomics
Average 90 stars, based on 1 article reviews
simax sirna design tool - by Bioz Stars, 2026-03
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online bioinformatics tool for the design of sirna target sequences  (Qiagen)
90
Qiagen online bioinformatics tool for the design of sirna target sequences
(A) H1-0 expression determined by RT-qPCR and representative Western Blot of REH cells treated for 48 hours with a non-targeting <t>siRNA</t> pool (siCtrl) or H1-0 -targeting siRNA pools siH1-0_1 or siH1- 0_2. Data is presented as the mean ± standard deviation. (B) Enrichment map of gene sets enriched in siCtrl REH cells compared to <t>siRNA-mediated</t> <t>knockdown</t> of H1-0 (cut-offs: p<0.005, false discovery rate (FDR) q-value<0.1) using the canonical pathways gene set collection (Human MSigDB Collections). No significantly enriched gene sets were found in siH1-0 REH cells using the indicated cut-offs. Groups of similar pathways are indicated. (C) Ingenuity Pathway analysis (IPA, QIAGEN) of upstream regulators significantly enriched in both siH1-0_1 versus siCtrl and siH1-0_2 versus siCtrl (p<0.05). (D) GSEA results of siH1-0 versus siCtrl using a published geneset of 103 significantly upregulated genes in both REH and AT-2 cells upon ETV6::RUNX1 knockdown (cut-offs: log2 fold change >0.9 and adjusted p<0.05). Normalized enrichment score (NES) and FDR are indicated. (E) GSEA of siH1-0 versus siCtrl using the HALLMARK_P53_PATHWAY gene set derived from Human MSigDB Collections. (F) RNA expression levels of EPOR , RAG1 and MDM2 determined by RNA-seq in siCtrl and siH1-0 REH. (G) Pearson correlation of H1-0 expression with EPOR or RAG1 expression in ETV6::RUNX1 + BCP-ALL patient samples derived from the PeCan St. Jude cloud (n=87, ( ; )).
Online Bioinformatics Tool For The Design Of Sirna Target Sequences, supplied by Qiagen, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/online bioinformatics tool for the design of sirna target sequences/product/Qiagen
Average 90 stars, based on 1 article reviews
online bioinformatics tool for the design of sirna target sequences - by Bioz Stars, 2026-03
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sirna and shrna design tool  (Shanghai GenePharma)
90
Shanghai GenePharma sirna and shrna design tool
(A) H1-0 expression determined by RT-qPCR and representative Western Blot of REH cells treated for 48 hours with a non-targeting <t>siRNA</t> pool (siCtrl) or H1-0 -targeting siRNA pools siH1-0_1 or siH1- 0_2. Data is presented as the mean ± standard deviation. (B) Enrichment map of gene sets enriched in siCtrl REH cells compared to <t>siRNA-mediated</t> <t>knockdown</t> of H1-0 (cut-offs: p<0.005, false discovery rate (FDR) q-value<0.1) using the canonical pathways gene set collection (Human MSigDB Collections). No significantly enriched gene sets were found in siH1-0 REH cells using the indicated cut-offs. Groups of similar pathways are indicated. (C) Ingenuity Pathway analysis (IPA, QIAGEN) of upstream regulators significantly enriched in both siH1-0_1 versus siCtrl and siH1-0_2 versus siCtrl (p<0.05). (D) GSEA results of siH1-0 versus siCtrl using a published geneset of 103 significantly upregulated genes in both REH and AT-2 cells upon ETV6::RUNX1 knockdown (cut-offs: log2 fold change >0.9 and adjusted p<0.05). Normalized enrichment score (NES) and FDR are indicated. (E) GSEA of siH1-0 versus siCtrl using the HALLMARK_P53_PATHWAY gene set derived from Human MSigDB Collections. (F) RNA expression levels of EPOR , RAG1 and MDM2 determined by RNA-seq in siCtrl and siH1-0 REH. (G) Pearson correlation of H1-0 expression with EPOR or RAG1 expression in ETV6::RUNX1 + BCP-ALL patient samples derived from the PeCan St. Jude cloud (n=87, ( ; )).
Sirna And Shrna Design Tool, supplied by Shanghai GenePharma, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/sirna and shrna design tool/product/Shanghai GenePharma
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sirna and shrna design tool - by Bioz Stars, 2026-03
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Image Search Results


(A) H1-0 expression determined by RT-qPCR and representative Western Blot of REH cells treated for 48 hours with a non-targeting siRNA pool (siCtrl) or H1-0 -targeting siRNA pools siH1-0_1 or siH1- 0_2. Data is presented as the mean ± standard deviation. (B) Enrichment map of gene sets enriched in siCtrl REH cells compared to siRNA-mediated knockdown of H1-0 (cut-offs: p<0.005, false discovery rate (FDR) q-value<0.1) using the canonical pathways gene set collection (Human MSigDB Collections). No significantly enriched gene sets were found in siH1-0 REH cells using the indicated cut-offs. Groups of similar pathways are indicated. (C) Ingenuity Pathway analysis (IPA, QIAGEN) of upstream regulators significantly enriched in both siH1-0_1 versus siCtrl and siH1-0_2 versus siCtrl (p<0.05). (D) GSEA results of siH1-0 versus siCtrl using a published geneset of 103 significantly upregulated genes in both REH and AT-2 cells upon ETV6::RUNX1 knockdown (cut-offs: log2 fold change >0.9 and adjusted p<0.05). Normalized enrichment score (NES) and FDR are indicated. (E) GSEA of siH1-0 versus siCtrl using the HALLMARK_P53_PATHWAY gene set derived from Human MSigDB Collections. (F) RNA expression levels of EPOR , RAG1 and MDM2 determined by RNA-seq in siCtrl and siH1-0 REH. (G) Pearson correlation of H1-0 expression with EPOR or RAG1 expression in ETV6::RUNX1 + BCP-ALL patient samples derived from the PeCan St. Jude cloud (n=87, ( ; )).

Journal: bioRxiv

Article Title: Linker histone H1-0 is a specific mediator of the repressive ETV6::RUNX1 transcriptional landscape

doi: 10.1101/2024.06.28.601221

Figure Lengend Snippet: (A) H1-0 expression determined by RT-qPCR and representative Western Blot of REH cells treated for 48 hours with a non-targeting siRNA pool (siCtrl) or H1-0 -targeting siRNA pools siH1-0_1 or siH1- 0_2. Data is presented as the mean ± standard deviation. (B) Enrichment map of gene sets enriched in siCtrl REH cells compared to siRNA-mediated knockdown of H1-0 (cut-offs: p<0.005, false discovery rate (FDR) q-value<0.1) using the canonical pathways gene set collection (Human MSigDB Collections). No significantly enriched gene sets were found in siH1-0 REH cells using the indicated cut-offs. Groups of similar pathways are indicated. (C) Ingenuity Pathway analysis (IPA, QIAGEN) of upstream regulators significantly enriched in both siH1-0_1 versus siCtrl and siH1-0_2 versus siCtrl (p<0.05). (D) GSEA results of siH1-0 versus siCtrl using a published geneset of 103 significantly upregulated genes in both REH and AT-2 cells upon ETV6::RUNX1 knockdown (cut-offs: log2 fold change >0.9 and adjusted p<0.05). Normalized enrichment score (NES) and FDR are indicated. (E) GSEA of siH1-0 versus siCtrl using the HALLMARK_P53_PATHWAY gene set derived from Human MSigDB Collections. (F) RNA expression levels of EPOR , RAG1 and MDM2 determined by RNA-seq in siCtrl and siH1-0 REH. (G) Pearson correlation of H1-0 expression with EPOR or RAG1 expression in ETV6::RUNX1 + BCP-ALL patient samples derived from the PeCan St. Jude cloud (n=87, ( ; )).

Article Snippet: Specific siRNA sequences for knockdown of H1-0 in REH cells were designed using the Eurofins siRNA design tool ( https://eurofinsgenomics.eu/en/ecom/tools/sirna-design/ ) and purchased from Eurofins Genomics.

Techniques: Expressing, Quantitative RT-PCR, Western Blot, Standard Deviation, Knockdown, Derivative Assay, RNA Expression, RNA Sequencing Assay